8K0I

Human collagen prolyl processing enzyme complex, P3H1/CRTAP/PPIB heterotrimer, in its dual-ternary state

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (A, a)	Prolyl 3-hydroxylase 1	polymer	736	83485.7	2	UniProt (Q32P28) Pfam (PF23557) Pfam (PF13640)	Homo sapiens (human)	Growth suppressor 1,Leucine- and proline-enriched proteoglycan 1,Leprecan-1
2	B, E (B, b)	Cartilage-associated protein	polymer	442	50749.2	2	UniProt (O75718) Pfam (PF23557)	Homo sapiens (human)
3	C, F (C, c)	Peptidyl-prolyl cis-trans isomerase B	polymer	256	28669.6	2	UniProt (P23284) Pfam (PF00160)	Homo sapiens (human)	PPIase B,CYP-S1,Cyclophilin B,Rotamase B,S-cyclophilin,SCYLP
4	G, H, I, J, K... (A, B, a, b)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	6	Chemie (NAG)

Sequence modifications

B, b: 1 - 401 (UniProt: O75718)

PDB	External Database	Details
Ala 402	-	expression tag
Ala 403	-	expression tag
Ala 404	-	expression tag
Leu 405	-	expression tag
Glu 406	-	expression tag
Val 407	-	expression tag
Leu 408	-	expression tag
Phe 409	-	expression tag
Gln 410	-	expression tag
Gly 411	-	expression tag
Pro 412	-	expression tag
Ser 413	-	expression tag
Ala 414	-	expression tag
Trp 415	-	expression tag
Ser 416	-	expression tag
His 417	-	expression tag
Pro 418	-	expression tag
Gln 419	-	expression tag
Phe 420	-	expression tag
Glu 421	-	expression tag
Lys 422	-	expression tag
Gly 423	-	expression tag
Gly 424	-	expression tag
Gly 425	-	expression tag
Ser 426	-	expression tag
Gly 427	-	expression tag
Gly 428	-	expression tag
Gly 429	-	expression tag
Ser 430	-	expression tag
Gly 431	-	expression tag
Gly 432	-	expression tag
Ser 433	-	expression tag
Ala 434	-	expression tag
Trp 435	-	expression tag
Ser 436	-	expression tag
His 437	-	expression tag
Pro 438	-	expression tag
Gln 439	-	expression tag
Phe 440	-	expression tag
Glu 441	-	expression tag
Lys 442	-	expression tag

C, c: -31 - 184 (UniProt: P23284)

PDB	External Database	Details
Ala 185	-	expression tag
Ala 186	-	expression tag
Ala 187	-	expression tag
Glu 188	-	expression tag
Asn 189	-	expression tag
Leu 190	-	expression tag
Tyr 191	-	expression tag
Phe 192	-	expression tag
Gln 193	-	expression tag
Gly 194	-	expression tag
Asp 195	-	expression tag
Tyr 196	-	expression tag
Lys 197	-	expression tag
Asp 198	-	expression tag
His 199	-	expression tag
Asp 200	-	expression tag
Gly 201	-	expression tag
Asp 202	-	expression tag
Tyr 203	-	expression tag
Lys 204	-	expression tag
Asp 205	-	expression tag
His 206	-	expression tag
Asp 207	-	expression tag
Ile 208	-	expression tag
Asp 209	-	expression tag
Tyr 210	-	expression tag
Lys 211	-	expression tag
Asp 212	-	expression tag
Asp 213	-	expression tag
Asp 214	-	expression tag
Asp 215	-	expression tag
Lys 216	-	expression tag
His 217	-	expression tag
His 218	-	expression tag
His 219	-	expression tag
His 220	-	expression tag
His 221	-	expression tag
His 222	-	expression tag
His 223	-	expression tag
His 224	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	325809.0
Non-Polymers*	Number of molecules	6
	Total formula weight	1327.2
All*	Total formula weight	327136.3

*Water molecules are not included.