8JZX

SLC15A4 inhibitor complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	SLC15A4-ALFA tag-SLC15A4-twin strep tag fusion protein	polymer	581	62274.2	2	UniProt (Q8N697) Pfam (PF00854)	Homo sapiens (human)
2	C, G (A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
3	D, F, H, I (A, B)	CHOLESTEROL	non-polymer		386.7	4	Chemie (CLR)
4	E, J (A, B)	2-(4-ethoxyphenyl)-N-[3-[(2R)-2-methylpiperidin-1-yl]propyl]quinoline-4-carboxamide	non-polymer		431.6	2	Chemie (Q09)

Sequence modifications

A, B: 1 - 290 (UniProt: Q8N697)
A, B: 291 - 303 (PDB: 8JZX)
A, B: 304 - 577 (UniProt: Q8N697)
A, B: 578 - 619 (PDB: 8JZX)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	124548.5
Non-Polymers*	Number of molecules	8
	Total formula weight	2852.2
All*	Total formula weight	127400.7

*Water molecules are not included.