8JXL

Human 3-methylcrotonyl-CoA carboxylase in MCCU state with MCoA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B, A, D, G, I...	Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial	polymer	563	61406.0	6	UniProt (Q9HCC0) Pfam (PF01039) In PDB	Homo sapiens (human)	MCCase subunit beta,3-methylcrotonyl-CoA carboxylase 2,3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit,3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta
2	F, C, E, H, J...	Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial	polymer	725	80584.0	6	UniProt (Q96RQ3) Pfam (PF00289) Pfam (PF02786) Pfam (PF02785) Pfam (PF00364) In PDB	Homo sapiens (human)	MCCase subunit alpha,3-methylcrotonyl-CoA carboxylase 1,3-methylcrotonyl-CoA carboxylase biotin-containing subunit,3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha
3	B, A, D, G, I...	~{S}-[2-[3-[[(2~{R})-4-[[[(2~{S},3~{S},4~{S},5~{S})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyl] 3-methylbut-2-enethioate	non-polymer		849.6	6	Chemie (TW3)
4	F, C, E, H, J...	5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL	non-polymer		228.3	6	Chemie (BTI)

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	851940.3
Non-Polymers*	Number of molecules	12
	Total formula weight	6467.7
All*	Total formula weight	858407.9

*Water molecules are not included.