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8JVL

Identification and characterization of inhibitors covalently modifying catalytic cysteine of UBE2T and blocking ubiquitin transfer

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Ubiquitin-conjugating enzyme E2 Tpolymer15617830.61UniProt (Q9NPD8)
Pfam (PF00179)
Homo sapiens (human)E2 ubiquitin-conjugating enzyme T,Ubiquitin carrier protein T,Ubiquitin-protein ligase T
2B
(A)
1-(4-methoxyphenyl)-1,2,3,4-tetrazolenon-polymer176.21Chemie (V5L)
3C
(A)
1,2-ETHANEDIOLnon-polymer62.11Chemie (EDO)
4D
(A)
waterwater18.0104Chemie (HOH)
Sequence modifications
A: 1 - 154 (UniProt: Q9NPD8)
PDBExternal DatabaseDetails
Gly -1-expression tag
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight17830.6
Non-Polymers*Number of molecules2
Total formula weight238.2
All*Total formula weight18068.8
*Water molecules are not included.

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PDB entries from 2024-11-13

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