8JVE
Identification and characterization of inhibitors covalently modifying catalytic cysteine of UBE2T and blocking ubiquitin transfer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Ubiquitin-conjugating enzyme E2 T | polymer | 156 | 17830.6 | 1 | UniProt (Q9NPD8) Pfam (PF00179) In PDB | Homo sapiens (human) | E2 ubiquitin-conjugating enzyme T,Ubiquitin carrier protein T,Ubiquitin-protein ligase T |
| 2 | A | 1-(3-methoxyphenyl)-1,2,3,4-tetrazole | non-polymer | 176.2 | 1 | Chemie (V6C) | |||
| 3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | water | water | 18.0 | 123 | Chemie (HOH) |
Sequence modifications
A: 1 - 154 (UniProt: Q9NPD8)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17830.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 238.2 | |
| All* | Total formula weight | 18068.8 |
