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8JTV

hOCT1 in complex with metformin in inward occluded conformation

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Solute carrier family 22 member 1polymer56662569.21UniProt (O15245)
Pfam (PF00083)
Homo sapiens (human)Organic cation transporter 1,hOCT1
2B
(A)
Metforminnon-polymer129.21Chemie (MF8)
Sequence modifications
A: 1 - 554 (UniProt: O15245)
PDBExternal DatabaseDetails
Glu 555-expression tag
Asp 556-expression tag
Gln 557-expression tag
Val 558-expression tag
Asp 559-expression tag
Pro 560-expression tag
Arg 561-expression tag
Leu 562-expression tag
Ile 563-expression tag
Asp 564-expression tag
Gly 565-expression tag
Lys 566-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight62569.2
Non-Polymers*Number of molecules1
Total formula weight129.2
All*Total formula weight62698.3
*Water molecules are not included.

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PDB entries from 2026-01-14

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