8JR3
Crystal structure of Hendra Virus attachment(G) glycoprotein mutant S586N in complex with neutralizing antibody 14F8
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (E, F) | Glycoprotein G | polymer | 416 | 46807.1 | 2 | UniProt (O89343) Pfam (PF00423) | Hendra virus (isolate Horse/Autralia/Hendra/1994) | |
| 2 | C, E (A, B) | Heavy chain of neutralizing antibody 14F8 | polymer | 217 | 23066.9 | 2 | Mus musculus | ||
| 3 | D, F (D, C) | Light chain of neutralizing antibody 14F8 | polymer | 212 | 23287.0 | 2 | Mus musculus | ||
| 4 | G (G) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 5 | H, N, O (H, N, O) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 3 | In PDB GlyTouCan (G21290RB) | |||
| 6 | I, J, L, M (I, J, L, M) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 4 | In PDB GlyTouCan (G42666HT) | |||
| 7 | K (K) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 1 | In PDB GlyTouCan (G32152BH) | |||
| 8 | P (F) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) |
Sequence modifications
E, F: 188 - 603 (UniProt: O89343)
| PDB | External Database | Details |
|---|---|---|
| Asn 586 | Ser 586 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 186322.0 | |
| Branched | Number of molecules | 9 |
| Total formula weight | 4728.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 221.2 | |
| All* | Total formula weight | 191271.7 |
