8JR0
Cryo-EM structure of Mycobacterium tuberculosis ATP synthase in complex with TBAJ-587
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | ATP synthase subunit alpha | polymer | 549 | 59358.1 | 3 | UniProt (P9WPU7) Pfam (PF02874) Pfam (PF00006) Pfam (PF00306) | Mycobacterium tuberculosis | ATP synthase F1 sector subunit alpha,F-ATPase subunit alpha |
| 2 | D, E, F (D, E, F) | ATP synthase subunit beta | polymer | 486 | 53150.9 | 3 | UniProt (P9WPU5) Pfam (PF02874) Pfam (PF00006) Pfam (PF22919) | Mycobacterium tuberculosis | ATP synthase F1 sector subunit beta,F-ATPase subunit beta |
| 3 | G (G) | ATP synthase gamma chain | polymer | 305 | 33929.3 | 1 | UniProt (P9WPU9) Pfam (PF00231) | Mycobacterium tuberculosis | ATP synthase F1 sector gamma subunit,F-ATPase gamma subunit |
| 4 | H (H) | ATP synthase epsilon chain | polymer | 121 | 13149.7 | 1 | UniProt (P9WPV1) Pfam (PF02823) | Mycobacterium tuberculosis | ATP synthase F1 sector epsilon subunit,F-ATPase epsilon subunit |
| 5 | I, J, K, L, M... (1, 2, 3, 4, 5...) | ATP synthase subunit c | polymer | 81 | 8058.4 | 9 | UniProt (A0A045H4W8) Pfam (PF00137) UniProt (by SIFTS) (P9WPS1) | Mycobacterium tuberculosis | |
| 6 | R (a) | ATP synthase subunit a | polymer | 250 | 27488.4 | 1 | UniProt (A0A045J1C5) Pfam (PF00119) UniProt (by SIFTS) (P9WPV7) | Mycobacterium tuberculosis | ATP synthase F0 sector subunit a,F-ATPase subunit 6 |
| 7 | S (b) | ATP synthase subunit b | polymer | 171 | 18345.8 | 1 | UniProt (A0A045H294) Pfam (PF00430) UniProt (by SIFTS) (P9WPV5) | Mycobacterium tuberculosis | |
| 8 | T (d) | Multifunctional fusion protein | polymer | 446 | 48866.6 | 1 | UniProt (A0A045JVE3) Pfam (PF00430) Pfam (PF00213) UniProt (by SIFTS) (P9WPV3) | Mycobacterium tuberculosis | Mycobacterium tuberculosis ATP synthase subunit b-delta |
| 9 | U, W, Y (A, B, C) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 3 | Chemie (ATP) | |||
| 10 | BA, DA, V, X, Z (D, F, A, B, C) | MAGNESIUM ION | non-polymer | 24.3 | 5 | Chemie (MG) | |||
| 11 | AA, CA (D, F) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
| 12 | EA, FA, GA, HA, IA... (1, 4, 5, 6, 7...) | (1~{S},2~{S})-1-(6-bromanyl-2-methoxy-quinolin-3-yl)-2-(2,6-dimethoxypyridin-4-yl)-4-(dimethylamino)-1-(2-fluoranyl-3-methoxy-phenyl)butan-2-ol | non-polymer | 614.5 | 7 | Chemie (UTI) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 20 |
| Total formula weight | 551832.8 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 6799.0 | |
| All* | Total formula weight | 558631.7 |
