8JQR
Structure of human TRPV1 in complex with antagonist
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Transient receptor potential cation channel subfamily V member 1,PreScission Site,Green fluorescent protein | polymer | 1112 | 125297.7 | 4 | UniProt (Q8NER1) In PDB | Homo sapiens (human) | TrpV1,Capsaicin receptor,Osm-9-like TRP channel 1,OTRPC1,Vanilloid receptor 1 |
2 | A, B, C, D | 4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile | non-polymer | 305.3 | 4 | Chemie (EZI) | |||
3 | A, B, C, D | CHOLESTEROL | non-polymer | 386.7 | 4 | Chemie (CLR) |
Sequence modifications
A, B, C, D: 1 - 839 (UniProt: Q8NER1)
A, B, C, D: 843 - 850 (PDB: 8JQR)
A, B, C, D: 851 - 1112 (PDB: 8JQR)
PDB | External Database | Details |
---|---|---|
Ala 840 | - | linker |
Ala 841 | - | linker |
Ala 842 | - | linker |
A, B, C, D: 851 - 1112 (PDB: 8JQR)
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 501190.9 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 2767.9 | |
All* | Total formula weight | 503958.9 |