8JN9
Crystal structure of c-Src in complex with covalent inhibitor LW-Srci-8
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Proto-oncogene tyrosine-protein kinase Src | polymer | 536 | 59986.6 | 1 | UniProt (P12931) Pfam (PF00018) Pfam (PF00017) Pfam (PF07714) | Homo sapiens (human) | Proto-oncogene c-Src,pp60c-src,p60-Src |
| 2 | B (A) | N-[(1R)-1-[3,5-bis(fluoranyl)phenyl]-2-(cyclopentylamino)-2-oxidanylidene-ethyl]-N-cyclopropyl-prop-2-enamide | non-polymer | 348.4 | 1 | Chemie (UJ0) | |||
| 3 | C (A) | water | water | 18.0 | 5 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 59986.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 348.4 | |
| All* | Total formula weight | 60334.9 |
