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8JN9

Crystal structure of c-Src in complex with covalent inhibitor LW-Srci-8

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AProto-oncogene tyrosine-protein kinase Srcpolymer53659986.61UniProt (P12931)
Pfam (PF00018)
Pfam (PF00017)
Pfam (PF07714)
In PDB
Homo sapiens (human)Proto-oncogene c-Src,pp60c-src,p60-Src
2AN-[(1R)-1-[3,5-bis(fluoranyl)phenyl]-2-(cyclopentylamino)-2-oxidanylidene-ethyl]-N-cyclopropyl-prop-2-enamidenon-polymer348.41Chemie (UJ0)
3waterwater18.05Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight59986.6
Non-Polymers*Number of molecules1
Total formula weight348.4
All*Total formula weight60334.9
*Water molecules are not included.

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