8JLI

Cryo-EM structure of SV2A dimer in complex levetiracetam

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Synaptic vesicle glycoprotein 2A	polymer	750	83774.0	2	UniProt (Q7L0J3) Pfam (PF00083) In PDB	Homo sapiens (human)
2	A, B	(2S)-2-(2-oxidanylidenepyrrolidin-1-yl)butanamide	non-polymer		170.2	2	Chemie (UKX)

Sequence modifications

A, B: 2 - 742 (UniProt: Q7L0J3)

PDB	External Database	Details
Met -7	-	initiating methionine
Asp -6	-	expression tag
Tyr -5	-	expression tag
Lys -4	-	expression tag
Asp -3	-	expression tag
Asp -2	-	expression tag
Asp -1	-	expression tag
Asp 0	-	expression tag
Lys 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	167548.0
Non-Polymers*	Number of molecules	2
	Total formula weight	340.4
All*	Total formula weight	167888.4

*Water molecules are not included.