8JLI
Cryo-EM structure of SV2A dimer in complex levetiracetam
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Synaptic vesicle glycoprotein 2A | polymer | 750 | 83774.0 | 2 | UniProt (Q7L0J3) Pfam (PF00083) Pfam (PF07690) | Homo sapiens (human) | |
| 2 | C, D (A, B) | (2S)-2-(2-oxidanylidenepyrrolidin-1-yl)butanamide | non-polymer | 170.2 | 2 | Chemie (UKX) |
Sequence modifications
A, B: 2 - 742 (UniProt: Q7L0J3)
| PDB | External Database | Details |
|---|---|---|
| Met -7 | - | initiating methionine |
| Asp -6 | - | expression tag |
| Tyr -5 | - | expression tag |
| Lys -4 | - | expression tag |
| Asp -3 | - | expression tag |
| Asp -2 | - | expression tag |
| Asp -1 | - | expression tag |
| Asp 0 | - | expression tag |
| Lys 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 167548.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 340.4 | |
| All* | Total formula weight | 167888.4 |
