8JLI

Cryo-EM structure of SV2A dimer in complex levetiracetam

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005783	cellular_component	endoplasmic reticulum
A	0005886	cellular_component	plasma membrane
A	0005911	cellular_component	cell-cell junction
A	0006836	biological_process	neurotransmitter transport
A	0007268	biological_process	chemical synaptic transmission
A	0008021	cellular_component	synaptic vesicle
A	0016020	cellular_component	membrane
A	0016082	biological_process	synaptic vesicle priming
A	0019901	molecular_function	protein kinase binding
A	0022857	molecular_function	transmembrane transporter activity
A	0030672	cellular_component	synaptic vesicle membrane
A	0031410	cellular_component	cytoplasmic vesicle
A	0031594	cellular_component	neuromuscular junction
A	0043005	cellular_component	neuron projection
A	0048786	cellular_component	presynaptic active zone
A	0055085	biological_process	transmembrane transport
A	0098793	cellular_component	presynapse
A	0098978	cellular_component	glutamatergic synapse
A	0098982	cellular_component	GABA-ergic synapse
B	0005783	cellular_component	endoplasmic reticulum
B	0005886	cellular_component	plasma membrane
B	0005911	cellular_component	cell-cell junction
B	0006836	biological_process	neurotransmitter transport
B	0007268	biological_process	chemical synaptic transmission
B	0008021	cellular_component	synaptic vesicle
B	0016020	cellular_component	membrane
B	0016082	biological_process	synaptic vesicle priming
B	0019901	molecular_function	protein kinase binding
B	0022857	molecular_function	transmembrane transporter activity
B	0030672	cellular_component	synaptic vesicle membrane
B	0031410	cellular_component	cytoplasmic vesicle
B	0031594	cellular_component	neuromuscular junction
B	0043005	cellular_component	neuron projection
B	0048786	cellular_component	presynaptic active zone
B	0055085	biological_process	transmembrane transport
B	0098793	cellular_component	presynapse
B	0098978	cellular_component	glutamatergic synapse
B	0098982	cellular_component	GABA-ergic synapse

Functional Information from PROSITE/UniProt

site_id	PS00217
Number of Residues	26
Details	SUGAR_TRANSPORT_2 Sugar transport proteins signature 2. LsGVGiGGsipivfsYfsEflaqekR

Chain	Residue	Details
A	LEU264-ARG289

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	480
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	348
Details	Topological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	88
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q02563","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"Q9JIS5","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	6
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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