8JJ1
Cryo-EM structure of GluN1-2A NMDAR in complex with human Fab2G7 in two fab conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, F (H, E) | Fab 2G7 Heavy Chain | polymer | 253 | 26893.0 | 2 | Homo sapiens | ||
| 2 | B, D (A, C) | Glutamate receptor ionotropic, NMDA 2A | polymer | 841 | 94136.0 | 2 | UniProt (Q12879) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) | Homo sapiens (human) | GluN2A,Glutamate [NMDA] receptor subunit epsilon-1,N-methyl D-aspartate receptor subtype 2A,NMDAR2A,NR2A,hNR2A |
| 3 | C, E (B, D) | Glutamate receptor ionotropic, NMDA 1 | polymer | 847 | 95236.1 | 2 | UniProt (Q05586) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) | Homo sapiens (human) | GluN1,Glutamate [NMDA] receptor subunit zeta-1,N-methyl-D-aspartate receptor subunit NR1,NMD-R1 |
| 4 | G, H (F, G) | Fab 2G7 Light Chain | polymer | 234 | 25765.0 | 2 | Homo sapiens | ||
| 5 | I (I) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 6 | J, K, L, M, N... (A, B, C, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 11 | Chemie (NAG) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 484060.3 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 2433.3 | |
| All* | Total formula weight | 486918.0 |
