8JE5
Crystal Structure of Anopheles culicifacies Prolyl-tRNA Synthetase (AcPRS) in complex with Halofuginone
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | PROLYL-TRNA SYNTHETASE | polymer | 505 | 58101.0 | 2 | UniProt (A0A182M1F8) Pfam (PF00587) Pfam (PF03129) Pfam (PF09180) | Anopheles culicifacies | |
| 2 | C, H (A, B) | 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one | non-polymer | 414.7 | 2 | Chemie (HFG) | |||
| 3 | D, I (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | E, F, J (A, B) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 5 | G, K, L (A, B) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 6 | M, N (A, B) | water | water | 18.0 | 16 | Chemie (HOH) |
Sequence modifications
A, B: 1219 - 1722 (UniProt: A0A182M1F8)
| PDB | External Database | Details |
|---|---|---|
| Met 1218 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 116202.0 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1342.8 | |
| All* | Total formula weight | 117544.8 |
