8JAT
Crystal structure of the 3-ketodihydrosphingosine reductase TSC10 from Cryptococcus neoformans
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | 3-ketodihydrosphingosine reductase TSC10 | polymer | 275 | 29768.9 | 1 | UniProt (P0CR36) Pfam (PF00106) In PDB | Cryptococcus neoformans var. neoformans JEC21 | 3-dehydrosphinganine reductase,KDS reductase |
2 | A | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 1 | Chemie (NDP) | |||
3 | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
A: 29 - 293 (UniProt: P0CR36)
PDB | External Database | Details |
---|---|---|
Met 28 | - | initiating methionine |
Phe 190 | Tyr 190 | engineered mutation |
Ser 294 | - | expression tag |
Gly 295 | - | expression tag |
Ser 296 | - | expression tag |
His 297 | - | expression tag |
His 298 | - | expression tag |
His 299 | - | expression tag |
His 300 | - | expression tag |
His 301 | - | expression tag |
His 302 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 29768.9 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 745.4 | |
All* | Total formula weight | 30514.3 |