8JA7
Cryo-EM structure of Mycobacterium tuberculosis LpqY-SugABC in complex with trehalose
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Trehalose transport system permease protein SugA | polymer | 307 | 33041.8 | 1 | UniProt (P9WG03) Pfam (PF00528) | Mycobacterium tuberculosis H37Rv | |
| 2 | B (B) | Trehalose transport system permease protein SugB | polymer | 274 | 29145.5 | 1 | UniProt (P9WG01) Pfam (PF00528) | Mycobacterium tuberculosis H37Rv | |
| 3 | C (E) | Trehalose-binding lipoprotein LpqY | polymer | 468 | 49803.1 | 1 | UniProt (P9WGU9) Pfam (PF01547) | Mycobacterium tuberculosis H37Rv | SugABC transporter substrate-binding protein LpqY,SugABC transporter SBP LpqY |
| 4 | D, E (C, D) | Trehalose import ATP-binding protein SugC | polymer | 393 | 42964.1 | 2 | UniProt (P9WQI3) Pfam (PF00005) Pfam (PF17912) | Mycobacterium tuberculosis H37Rv | MtbSugC,Nucleotide-binding domain of SugABC transporter,NBD of SugABC transporter,SugABC transporter ATPase SugC |
| 5 | F (F) | alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose | branched | 342.3 | 1 | In PDB GlyTouCan (G92130SN) |
Sequence modifications
A: 2 - 307 (UniProt: P9WG03)
B: 2 - 274 (UniProt: P9WG01)
E: 2 - 468 (UniProt: P9WGU9)
| PDB | External Database | Details |
|---|---|---|
| Val 1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Val 1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Val 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 197918.6 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 342.3 | |
| All* | Total formula weight | 198260.9 |
