8JA7

Cryo-EM structure of Mycobacterium tuberculosis LpqY-SugABC in complex with trehalose

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005886	cellular_component	plasma membrane
A	0016020	cellular_component	membrane
A	0051701	biological_process	biological process involved in interaction with host
A	0055085	biological_process	transmembrane transport
B	0005886	cellular_component	plasma membrane
B	0016020	cellular_component	membrane
B	0051701	biological_process	biological process involved in interaction with host
B	0055085	biological_process	transmembrane transport
C	0000166	molecular_function	nucleotide binding
C	0005524	molecular_function	ATP binding
C	0005886	cellular_component	plasma membrane
C	0008643	biological_process	carbohydrate transport
C	0015574	molecular_function	trehalose transmembrane transporter activity
C	0015771	biological_process	trehalose transport
C	0016887	molecular_function	ATP hydrolysis activity
C	0034219	biological_process	carbohydrate transmembrane transport
C	0035796	cellular_component	ATP-binding cassette (ABC) transporter complex, transmembrane substrate-binding subunit-containing
C	0042802	molecular_function	identical protein binding
C	0042803	molecular_function	protein homodimerization activity
C	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
C	0043211	molecular_function	ABC-type carbohydrate transporter activity
C	0051701	biological_process	biological process involved in interaction with host
C	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
C	0055085	biological_process	transmembrane transport
C	0140359	molecular_function	ABC-type transporter activity
D	0000166	molecular_function	nucleotide binding
D	0005524	molecular_function	ATP binding
D	0005886	cellular_component	plasma membrane
D	0008643	biological_process	carbohydrate transport
D	0015574	molecular_function	trehalose transmembrane transporter activity
D	0015771	biological_process	trehalose transport
D	0016887	molecular_function	ATP hydrolysis activity
D	0034219	biological_process	carbohydrate transmembrane transport
D	0035796	cellular_component	ATP-binding cassette (ABC) transporter complex, transmembrane substrate-binding subunit-containing
D	0042802	molecular_function	identical protein binding
D	0042803	molecular_function	protein homodimerization activity
D	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
D	0043211	molecular_function	ABC-type carbohydrate transporter activity
D	0051701	biological_process	biological process involved in interaction with host
D	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
D	0055085	biological_process	transmembrane transport
D	0140359	molecular_function	ABC-type transporter activity

Functional Information from PROSITE/UniProt

site_id	PS00211
Number of Residues	15
Details	ABC_TRANSPORTER_1 ABC transporters family signature. LSGGQRQRVAMGRAI

Chain	Residue	Details
C	LEU135-ILE149

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	240
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"PROSITE-ProRule","id":"PRU00441","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	399
Details	Domain: {"description":"ABC transmembrane type-1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00441","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"35775983","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7WDA","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Lipidation: {"description":"S-diacylglycerol cysteine","evidences":[{"source":"PROSITE-ProRule","id":"PRU00303","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	462
Details	Domain: {"description":"ABC transporter","evidences":[{"source":"PROSITE-ProRule","id":"PRU00434","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	8
Details	Motif: {"description":"Helical C-loop; LSGGQ motif","evidences":[{"source":"PubMed","id":"32092417","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	14
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00434","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---