8J81
MDM2 bound with a peptoid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | E3 ubiquitin-protein ligase Mdm2 | polymer | 100 | 11510.5 | 1 | UniProt (Q00987) Pfam (PF02201) | Homo sapiens (human) | Double minute 2 protein,Hdm2,Oncoprotein Mdm2,RING-type E3 ubiquitin transferase Mdm2,p53-binding protein Mdm2 |
| 2 | B (A) | (2S)-2-[[(2S)-2-[(6-chloranyl-1H-indol-3-yl)methyl-[(2S)-2-[[(2S)-2-[ethanoyl-(phenylmethyl)amino]propanoyl]-methyl-amino]propanoyl]amino]propanoyl]-methyl-amino]-N-(3,3-dimethylbutyl)-N-[(2S)-1-oxidanylidene-1-piperazin-1-yl-propan-2-yl]propanamide | non-polymer | 849.5 | 1 | Chemie (UAC) | |||
| 3 | C, D, E, F, G... (A) | CHLORIDE ION | non-polymer | 35.5 | 7 | Chemie (CL) | |||
| 4 | J (A) | water | water | 18.0 | 82 | Chemie (HOH) |
Sequence modifications
A: 17 - 111 (UniProt: Q00987)
| PDB | External Database | Details |
|---|---|---|
| Gly 12 | - | expression tag |
| Pro 13 | - | expression tag |
| Leu 14 | - | expression tag |
| Gly 15 | - | expression tag |
| Ser 16 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 11510.5 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1097.7 | |
| All* | Total formula weight | 12608.1 |
