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8J74

Human high-affinity choline transporter CHT1 in the HC-3-bound outward-facing open conformation, dimeric state

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
High affinity choline transporter 1polymer58063239.12UniProt (Q9GZV3)
Pfam (PF00474)
Homo sapiens (human)Hemicholinium-3-sensitive choline transporter,CHT,Solute carrier family 5 member 7
2C, D
(E, F)
beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched586.52In PDB
GlyTouCan (G15407YE)
3E, K
(A, B)
CHOLESTEROL HEMISUCCINATEnon-polymer486.72Chemie (Y01)
PubChem (16219150)
PubChem (22210610)
PubChem (65082)
PubChem (363416)
PubChem (45489984)
PubChem (500055)
PubChem (60078761)
PubChem (57163942)
PubChem (73440805)
PubChem (89891013)
PubChem (13301926)
PubChem (13301927)
PubChem (99567469)
PubChem (99567468)
PubChem (124427194)
PubChem (124897021)
PubChem (124897020)
PubChem (10005657)
PubChem (130340716)
PubChem (11969853)
PubChem (124301053)
PubChem (124302591)
PubChem (124303794)
PubChem (124421343)
PubChem (124427195)
PubChem (137392566)
PubChem (137496323)
PubChem (124914595)
PubChem (124914596)
PubChem (131705526)
PubChem (155804219)
PubChem (137332121)
PubChem (137496357)
PubChem (146157332)
PubChem (169132514)
PubChem (154929912)
PubChem (155199678)
PubChem (156327905)
PubChem (156426247)
PubChem (156516588)
PubChem (166979870)
PubChem (167024614)
PubChem (169132513)
PubChem (170117245)
PubChem (172400028)
4F, I
(A, B)
Lauryl Maltose Neopentyl Glycolnon-polymer1005.22Chemie (AV0)
5G, J
(A, B)
HEXADECANEnon-polymer226.42Chemie (R16)
PubChem (11006)
6H, L
(A, B)
(2S,2'S)-2,2'-biphenyl-4,4'-diylbis(2-hydroxy-4,4-dimethylmorpholin-4-ium)non-polymer414.52Chemie (HC6)
PubChem (3585)
PubChem (25023712)
PubChem (6603861)
PubChem (6604237)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight126478.3
BranchedNumber of molecules2
Total formula weight1173.1
Non-Polymers*Number of molecules8
Total formula weight4265.8
All*Total formula weight131917.2
*Water molecules are not included.

251422

PDB entries from 2026-04-01

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