8J3T
Complex structure of human cytomegalovirus protease and a non-covalent small-molecule ligand
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Assemblin | polymer | 263 | 29130.7 | 2 | UniProt (A0A0G2TMR2) Pfam (PF00716) UniProt (by SIFTS) (P16753) In PDB | Human betaherpesvirus 5 | Protease |
2 | A, B | (4R)-1-[1-[(S)-[1-cyclopentyl-3-(2-methylphenyl)pyrazol-4-yl]-(4-methylphenyl)methyl]-2-oxidanylidene-pyridin-3-yl]-3-methyl-2-oxidanylidene-N-(3-oxidanylidene-2-azabicyclo[2.2.2]octan-4-yl)imidazolidine-4-carboxamide | non-polymer | 687.8 | 2 | Chemie (T1F) | |||
3 | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 256 (UniProt: A0A0G2TMR2)
PDB | External Database | Details |
---|---|---|
Met -6 | - | initiating methionine |
His -5 | - | expression tag |
His -4 | - | expression tag |
His -3 | - | expression tag |
His -2 | - | expression tag |
His -1 | - | expression tag |
His 0 | - | expression tag |
Gln 143 | Ala 143 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 58261.4 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 1375.7 | |
All* | Total formula weight | 59637.0 |