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8J1H

Agonist1 and Ruthenium Red bound state of mTRPV4

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(C, D, B, A)
Transient receptor potential cation channel subfamily V member 4polymer66575666.64UniProt (Q9EPK8)
Pfam (PF00023)
Pfam (PF00520)
Mus musculus (house mouse)TrpV4,Osm-9-like TRP channel 4,OTRPC4,Transient receptor potential protein 12,TRP12,Vanilloid receptor-like channel 2,Vanilloid receptor-like protein 2,Vanilloid receptor-related osmotically-activated channel,VR-OAC
2E, F, G, H
(C, D, B, A)
8-fluoranyl-3-[4-(4-fluoranylphenoxy)phenyl]-2-(4-methylpiperazin-1-yl)quinazolin-4-onenon-polymer448.54Chemie (9QM)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight302666.4
Non-Polymers*Number of molecules4
Total formula weight1793.9
All*Total formula weight304460.2
*Water molecules are not included.

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PDB entries from 2025-06-18

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