8J1H
Agonist1 and Ruthenium Red bound state of mTRPV4
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D (C, D, B, A) | Transient receptor potential cation channel subfamily V member 4 | polymer | 665 | 75666.6 | 4 | UniProt (Q9EPK8) Pfam (PF00023) Pfam (PF00520) | Mus musculus (house mouse) | TrpV4,Osm-9-like TRP channel 4,OTRPC4,Transient receptor potential protein 12,TRP12,Vanilloid receptor-like channel 2,Vanilloid receptor-like protein 2,Vanilloid receptor-related osmotically-activated channel,VR-OAC |
2 | E, F, G, H (C, D, B, A) | 8-fluoranyl-3-[4-(4-fluoranylphenoxy)phenyl]-2-(4-methylpiperazin-1-yl)quinazolin-4-one | non-polymer | 448.5 | 4 | Chemie (9QM) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 302666.4 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1793.9 | |
All* | Total formula weight | 304460.2 |