8IZ9

cryo-EM structure of PGE1-bound hMRP4

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	ATP-binding cassette sub-family C member 4	polymer	1357	153171.4	1	UniProt (O15439) Pfam (PF00664) Pfam (PF00005) In PDB	Homo sapiens (human)	MRP/cMOAT-related ABC transporter,Multi-specific organic anion transporter B,MOAT-B,Multidrug resistance-associated protein 4
2	A	7-[(1R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]heptanoic acid	non-polymer		354.5	1	Chemie (XPG)

Sequence modifications

A: 1 - 1325 (UniProt: O15439)

PDB	External Database	Details
Leu 1326	-	expression tag
Glu 1327	-	expression tag
Gly 1328	-	expression tag
Gly 1329	-	expression tag
Gly 1330	-	expression tag
Ser 1331	-	expression tag
Gly 1332	-	expression tag
Gly 1333	-	expression tag
Gly 1334	-	expression tag
Ser 1335	-	expression tag
Asp 1336	-	expression tag
Tyr 1337	-	expression tag
Lys 1338	-	expression tag
Asp 1339	-	expression tag
His 1340	-	expression tag
Asp 1341	-	expression tag
Gly 1342	-	expression tag
Asp 1343	-	expression tag
Tyr 1344	-	expression tag
Lys 1345	-	expression tag
Asp 1346	-	expression tag
His 1347	-	expression tag
Asp 1348	-	expression tag
Ile 1349	-	expression tag
Asp 1350	-	expression tag
Tyr 1351	-	expression tag
Lys 1352	-	expression tag
Asp 1353	-	expression tag
Asp 1354	-	expression tag
Asp 1355	-	expression tag
Asp 1356	-	expression tag
Lys 1357	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	153171.4
Non-Polymers*	Number of molecules	1
	Total formula weight	354.5
All*	Total formula weight	153525.8

*Water molecules are not included.