8IYS
TUG891-bound FFAR4 in complex with Gq
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Guanine nucleotide-binding protein G(q) subunit alpha | polymer | 357 | 41523.2 | 1 | UniProt (P50148) Pfam (PF00503) | Homo sapiens (human) | Guanine nucleotide-binding protein alpha-q |
| 2 | B (B) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 345 | 37915.5 | 1 | UniProt (P62873) Pfam (PF25391) | Homo sapiens (human) | Transducin beta chain 1 |
| 3 | C (E) | scFv16 | polymer | 247 | 26277.3 | 1 | Homo sapiens | ||
| 4 | D (G) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 71 | 7861.1 | 1 | UniProt (P59768) Pfam (PF00631) | Homo sapiens (human) | G gamma-I |
| 5 | E (R) | Free fatty acid receptor 4 | polymer | 361 | 40533.2 | 1 | UniProt (Q5NUL3) Pfam (PF00001) | Homo sapiens (human) | G-protein coupled receptor 120,G-protein coupled receptor 129,G-protein coupled receptor GT01,G-protein coupled receptor PGR4,Omega-3 fatty acid receptor 1 |
| 6 | F (A) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 7 | G (R) | 3-{4-[(4-fluoro-4'-methyl[1,1'-biphenyl]-2-yl)methoxy]phenyl}propanoic acid | non-polymer | 364.4 | 1 | Chemie (YN9) PubChem (57522038) |
Sequence modifications
A: 30 - 357 (UniProt: P50148)
B: 2 - 340 (UniProt: P62873)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Gly 2 | - | expression tag |
| Cys 3 | - | expression tag |
| Thr 4 | - | expression tag |
| Leu 5 | - | expression tag |
| Ser 6 | - | expression tag |
| Ala 7 | - | expression tag |
| Glu 8 | - | expression tag |
| Asp 9 | - | expression tag |
| Lys 10 | - | expression tag |
| Ala 11 | - | expression tag |
| Ala 12 | - | expression tag |
| Val 13 | - | expression tag |
| Glu 14 | - | expression tag |
| Arg 15 | - | expression tag |
| Ser 16 | - | expression tag |
| Lys 17 | - | expression tag |
| Met 18 | - | expression tag |
| Ile 19 | - | expression tag |
| Asp 20 | - | expression tag |
| Arg 21 | - | expression tag |
| Asn 22 | - | expression tag |
| Leu 23 | - | expression tag |
| Arg 24 | - | expression tag |
| Glu 25 | - | expression tag |
| Asp 26 | - | expression tag |
| Gly 27 | - | expression tag |
| Glu 28 | - | expression tag |
| Lys 29 | - | expression tag |
| Ala 333 | - | insertion |
| Ala 334 | - | insertion |
| Ala 335 | - | insertion |
| Ala 336 | - | insertion |
| PDB | External Database | Details |
|---|---|---|
| Met -4 | - | initiating methionine |
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| Leu -1 | - | expression tag |
| Leu 0 | - | expression tag |
| Gln 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 154110.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 807.6 | |
| All* | Total formula weight | 154918.0 |
