8IYS
TUG891-bound FFAR4 in complex with Gq
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Guanine nucleotide-binding protein G(q) subunit alpha | polymer | 357 | 41523.2 | 1 | UniProt (P50148) Pfam (PF00503) In PDB | Homo sapiens (human) | Guanine nucleotide-binding protein alpha-q |
2 | B | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 345 | 37915.5 | 1 | UniProt (P62873) Pfam (PF00400) In PDB | Homo sapiens (human) | Transducin beta chain 1 |
3 | E | scFv16 | polymer | 247 | 26277.3 | 1 | Homo sapiens | ||
4 | G | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 71 | 7861.1 | 1 | UniProt (P59768) Pfam (PF00631) In PDB | Homo sapiens (human) | G gamma-I |
5 | R | Free fatty acid receptor 4 | polymer | 361 | 40533.2 | 1 | UniProt (Q5NUL3) Pfam (PF00001) In PDB | Homo sapiens (human) | G-protein coupled receptor 120,G-protein coupled receptor 129,G-protein coupled receptor GT01,G-protein coupled receptor PGR4,Omega-3 fatty acid receptor 1 |
6 | A | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
7 | R | 3-{4-[(4-fluoro-4'-methyl[1,1'-biphenyl]-2-yl)methoxy]phenyl}propanoic acid | non-polymer | 364.4 | 1 | Chemie (YN9) |
Sequence modifications
A: 30 - 357 (UniProt: P50148)
B: 2 - 340 (UniProt: P62873)
PDB | External Database | Details |
---|---|---|
Met 1 | - | initiating methionine |
Gly 2 | - | expression tag |
Cys 3 | - | expression tag |
Thr 4 | - | expression tag |
Leu 5 | - | expression tag |
Ser 6 | - | expression tag |
Ala 7 | - | expression tag |
Glu 8 | - | expression tag |
Asp 9 | - | expression tag |
Lys 10 | - | expression tag |
Ala 11 | - | expression tag |
Ala 12 | - | expression tag |
Val 13 | - | expression tag |
Glu 14 | - | expression tag |
Arg 15 | - | expression tag |
Ser 16 | - | expression tag |
Lys 17 | - | expression tag |
Met 18 | - | expression tag |
Ile 19 | - | expression tag |
Asp 20 | - | expression tag |
Arg 21 | - | expression tag |
Asn 22 | - | expression tag |
Leu 23 | - | expression tag |
Arg 24 | - | expression tag |
Glu 25 | - | expression tag |
Asp 26 | - | expression tag |
Gly 27 | - | expression tag |
Glu 28 | - | expression tag |
Lys 29 | - | expression tag |
Ala 333 | - | insertion |
Ala 334 | - | insertion |
Ala 335 | - | insertion |
Ala 336 | - | insertion |
PDB | External Database | Details |
---|---|---|
Met -4 | - | initiating methionine |
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
Leu -1 | - | expression tag |
Leu 0 | - | expression tag |
Gln 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 154110.3 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 807.6 | |
All* | Total formula weight | 154918.0 |