8IYS
TUG891-bound FFAR4 in complex with Gq
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Guanine nucleotide-binding protein G(q) subunit alpha | polymer | 357 | 41523.2 | 1 | UniProt (P50148) Pfam (PF00503) | Homo sapiens (human) | Guanine nucleotide-binding protein alpha-q |
| 2 | B (B) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 345 | 37915.5 | 1 | UniProt (P62873) Pfam (PF25391) | Homo sapiens (human) | Transducin beta chain 1 |
| 3 | C (E) | scFv16 | polymer | 247 | 26277.3 | 1 | Homo sapiens | ||
| 4 | D (G) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 71 | 7861.1 | 1 | UniProt (P59768) Pfam (PF00631) | Homo sapiens (human) | G gamma-I |
| 5 | E (R) | Free fatty acid receptor 4 | polymer | 361 | 40533.2 | 1 | UniProt (Q5NUL3) Pfam (PF00001) | Homo sapiens (human) | G-protein coupled receptor 120,G-protein coupled receptor 129,G-protein coupled receptor GT01,G-protein coupled receptor PGR4,Omega-3 fatty acid receptor 1 |
| 6 | F (A) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 7 | G (R) | 3-{4-[(4-fluoro-4'-methyl[1,1'-biphenyl]-2-yl)methoxy]phenyl}propanoic acid | non-polymer | 364.4 | 1 | Chemie (YN9) PubChem (57522038) |
Sequence modifications
A: 30 - 357 (UniProt: P50148)
B: 2 - 340 (UniProt: P62873)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Gly 2 | - | expression tag |
| Cys 3 | - | expression tag |
| Thr 4 | - | expression tag |
| Leu 5 | - | expression tag |
| Ser 6 | - | expression tag |
| Ala 7 | - | expression tag |
| Glu 8 | - | expression tag |
| Asp 9 | - | expression tag |
| Lys 10 | - | expression tag |
| Ala 11 | - | expression tag |
| Ala 12 | - | expression tag |
| Val 13 | - | expression tag |
| Glu 14 | - | expression tag |
| Arg 15 | - | expression tag |
| Ser 16 | - | expression tag |
| Lys 17 | - | expression tag |
| Met 18 | - | expression tag |
| Ile 19 | - | expression tag |
| Asp 20 | - | expression tag |
| Arg 21 | - | expression tag |
| Asn 22 | - | expression tag |
| Leu 23 | - | expression tag |
| Arg 24 | - | expression tag |
| Glu 25 | - | expression tag |
| Asp 26 | - | expression tag |
| Gly 27 | - | expression tag |
| Glu 28 | - | expression tag |
| Lys 29 | - | expression tag |
| Ala 333 | - | insertion |
| Ala 334 | - | insertion |
| Ala 335 | - | insertion |
| Ala 336 | - | insertion |
| PDB | External Database | Details |
|---|---|---|
| Met -4 | - | initiating methionine |
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| Leu -1 | - | expression tag |
| Leu 0 | - | expression tag |
| Gln 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 154110.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 807.6 | |
| All* | Total formula weight | 154918.0 |
