8IXO
Intermediate structure of mPIEZO1-S2472E
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (F, A, B) | Piezo-type mechanosensitive ion channel component 1 | polymer | 2547 | 292362.7 | 3 | UniProt (E2JF22) Pfam (PF24871) Pfam (PF15917) Pfam (PF23188) Pfam (PF24874) Pfam (PF12166) | Mus musculus (house mouse) | Protein FAM38A |
| 2 | D, E, I, J, N... (F, A, B) | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL | non-polymer | 767.1 | 6 | Chemie (PLX) | |||
| 3 | F, G, K, L, P... (F, A, B) | O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine | non-polymer | 792.1 | 6 | Chemie (P5S) | |||
| 4 | H, M, R (F, A, B) | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine | non-polymer | 744.0 | 3 | Chemie (PEE) |
Sequence modifications
F, A, B: 1 - 2547 (UniProt: E2JF22)
| PDB | External Database | Details |
|---|---|---|
| Glu 2472 | Ser 2472 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 877088.1 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 11587.3 | |
| All* | Total formula weight | 888675.4 |
