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8IXE

GMPCPP-Alpha1C/Beta2A-microtubule decorated with kinesin seam region

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, D, G, J
(H, B, J, K)
Tubulin alpha-1C chainpolymer45550791.04UniProt (P68373)
Pfam (PF00091)
Pfam (PF03953)
Mus musculus (house mouse)Alpha-tubulin 6,Alpha-tubulin isotype M-alpha-6,Tubulin alpha-6 chain
2B, E, H, K
(W, R, Z, a)
Tubulin beta-2A chainpolymer45751151.04UniProt (Q7TMM9)
Pfam (PF00091)
Pfam (PF03953)
Mus musculus (house mouse)
3C, F, I, L
(l, h, p, q)
Kinesin-1 heavy chainpolymer37241721.14UniProt (P33176)
Pfam (PF00225)
Homo sapiens (human)Conventional kinesin heavy chain,Ubiquitous kinesin heavy chain,UKHC
4M, P, S, V
(W, R, Z, a)
GUANOSINE-5'-TRIPHOSPHATEnon-polymer523.24Chemie (GTP)
5N, Q, T, W
(W, R, Z, a)
PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTERnon-polymer521.24Chemie (G2P)
6O, R, U, X
(l, h, p, q)
ADENOSINE-5'-TRIPHOSPHATEnon-polymer507.24Chemie (ATP)
Sequence modifications
H, B, J, K: 1 - 455 (UniProt: P68373)
PDBExternal DatabaseDetails
His 43-insertion
His 44-insertion
His 45-insertion
His 46-insertion
His 47-insertion
His 48-insertion
W, R, Z, a: 1 - 445 (UniProt: Q7TMM9)
PDBExternal DatabaseDetails
Gly 446-expression tag
Gly 447-expression tag
Ser 448-expression tag
Gly 449-expression tag
Gly 450-expression tag
Asp 451-expression tag
Tyr 452-expression tag
Lys 453-expression tag
Asp 454-expression tag
Asp 455-expression tag
Asp 456-expression tag
Lys 457-expression tag
l, h, p, q: 1 - 349 (UniProt: P33176)
PDBExternal DatabaseDetails
Met -22-initiating methionine
Gly -21-expression tag
Ser -20-expression tag
Ser -19-expression tag
His -18-expression tag
His -17-expression tag
His -16-expression tag
His -15-expression tag
His -14-expression tag
His -13-expression tag
Ser -12-expression tag
Ser -11-expression tag
Gly -10-expression tag
Leu -9-expression tag
Val -8-expression tag
Pro -7-expression tag
Arg -6-expression tag
Gly -5-expression tag
Ser -4-expression tag
His -3-expression tag
Met -2-expression tag
Ala -1-expression tag
Ser 0-expression tag
Ala 236Glu 236conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains12
Total formula weight574652.3
Non-Polymers*Number of molecules12
Total formula weight6206.3
All*Total formula weight580858.6
*Water molecules are not included.

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PDB entries from 2025-06-11

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