8IVW

Crystal structure of NRP2 in complex with aNRP2-10 Fab fragment

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D, G, J (A, D, G, J)	Neuropilin-2	polymer	583	65954.9	4	UniProt (O60462) Pfam (PF00431) Pfam (PF00754)	Homo sapiens (human)	Vascular endothelial cell growth factor 165 receptor 2
2	B, E, H, K (B, E, H, K)	Heavy chian of antibody 10V8 Fab fragment	polymer	228	24704.6	4		Homo sapiens
3	C, F, I, L (C, F, I, L)	Light chain of antibody 10V8 Fab fragment	polymer	215	23441.0	4		Homo sapiens

Sequence modifications

A, D, G, J: 25 - 595 (UniProt: O60462)

PDB	External Database	Details
His 13	-	expression tag
His 14	-	expression tag
His 15	-	expression tag
His 16	-	expression tag
His 17	-	expression tag
His 18	-	expression tag
Glu 19	-	expression tag
Asn 20	-	expression tag
Leu 21	-	expression tag
Tyr 22	-	expression tag
Phe 23	-	expression tag
Gln 24	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	456402.0
All*	Total formula weight	456402.0

*Water molecules are not included.