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8IQF

Cryo-EM structure of the dimeric human CAF1-H3-H4 complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, F
(A, F)
Chromatin assembly factor 1 subunit Apolymer956107080.32UniProt (Q13111)
Pfam (PF15557)
Pfam (PF11600)
Pfam (PF12253)
Pfam (PF15539)
Homo sapiens (human)CAF-1 subunit A,Chromatin assembly factor I p150 subunit,CAF-I 150 kDa subunit,CAF-I p150,hp150
2B, G
(D, I)
Histone H3.1polymer13615437.22UniProt (P68431)
Pfam (PF00125)
Homo sapiens (human)Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l
3C, H
(E, J)
Histone H4polymer10311394.42UniProt (P62805)
Pfam (PF15511)
Homo sapiens (human)
4D, I
(C, H)
Histone-binding protein RBBP4polymer42547709.52UniProt (Q09028)
Pfam (PF00400)
Pfam (PF12265)
Homo sapiens (human)Chromatin assembly factor 1 subunit C,CAF-1 subunit C,Chromatin assembly factor I p48 subunit,CAF-I 48 kDa subunit,CAF-I p48,Nucleosome-remodeling factor subunit RBAP48,Retinoblastoma-binding protein 4,RBBP-4,Retinoblastoma-binding protein p48
5E, J
(B, G)
Chromatin assembly factor 1 subunit Bpolymer55961567.32UniProt (Q13112)
Pfam (PF00400)
Pfam (PF15512)
Homo sapiens (human)CAF-1 subunit B,Chromatin assembly factor I p60 subunit,CAF-I 60 kDa subunit,CAF-I p60,M-phase phosphoprotein 7
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains10
Total formula weight486377.6
All*Total formula weight486377.6
*Water molecules are not included.

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PDB entries from 2025-06-11

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