8IM3

Crystal structure of human HPPD complexed with compound a10

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	4-hydroxyphenylpyruvate dioxygenase	polymer	393	44996.3	6	UniProt (P32754) Pfam (PF00903)	Homo sapiens (human)	4-hydroxyphenylpyruvic acid oxidase,4HPPD,HPD,HPPDase
2	G, I, K, M, O... (A, B, C, D, E...)	COBALT (II) ION	non-polymer		58.9	6	Chemie (CO)
3	H, J, L, N, P... (A, B, C, D, E...)	[1,3-diethyl-2,2-bis(oxidanylidene)-2$l^{6},1,3-benzothiadiazol-5-yl]-(1-methyl-5-oxidanyl-pyrazol-4-yl)methanone	non-polymer		350.4	6	Chemie (92U)
4	S, T, U, V, W... (A, B, C, D, E...)	water	water		18.0	149	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	269977.5
Non-Polymers*	Number of molecules	12
	Total formula weight	2456.0
All*	Total formula weight	272433.5

*Water molecules are not included.