8IK0

Cryo-EM structure of Stimulator of interferon genes

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, F, D...	Stimulator of interferon genes protein,Immune protein Tsi3	polymer	490	55282.3	8	UniProt (E1C7U0) UniProt (Q9HYC4) Pfam (PF15009) Pfam (PF22211) In PDB	Gallus gallus (chicken)	STING,Transmembrane protein 173,Anti-toxin protein Tsi3

Sequence modifications

A, B, C, F, D, G, E, H: 1 - 342 (UniProt: E1C7U0)

PDB	External Database	Details
Thr 50	Ile 50	conflict
Arg 52	Ser 52	conflict
His 100	Tyr 100	conflict
Ile 187	Leu 187	conflict
Arg 343	-	linker
Glu 344	-	linker
Glu 345	-	linker
Tyr 346	-	linker
Met 347	-	linker
Val 348	-	linker
Leu 349	-	linker
Glu 350	-	linker
Val 351	-	linker
Leu 352	-	linker
Phe 353	-	linker
Gln 354	-	linker
Gly 355	-	linker
Pro 356	-	linker

A, B, C, F, D, G, E, H: 357 - 480 (UniProt: Q9HYC4)

PDB	External Database	Details
Ser 481	-	expression tag
Ser 482	-	expression tag
His 483	-	expression tag
His 484	-	expression tag
His 485	-	expression tag
His 486	-	expression tag
His 487	-	expression tag
His 488	-	expression tag
His 489	-	expression tag
His 490	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	442258.7
All*	Total formula weight	442258.7

*Water molecules are not included.