8IJ9

Crystal structure of the ELKS1/Rab6B complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Ras-related protein Rab-6B	polymer	173	19641.3	2	UniProt (P61294) Pfam (PF00071)	Mus musculus (house mouse)
2	C, D (C, D)	ELKS/Rab6-interacting/CAST family member 1	polymer	78	8925.2	2	UniProt (Q811U3)	Rattus norvegicus (Norway rat)	ERC-1,CAZ-associated structural protein 2,CAST2,Rab6-interacting protein 2
3	E, G (A, B)	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	2	Chemie (GTP) PubChem (177679032) PubChem (135400627) PubChem (135487750) PubChem (136088935) PubChem (136803486) PubChem (135398633) PubChem (135544356) PubChem (135547949) PubChem (135600366) PubChem (135749822) PubChem (136005188) PubChem (136073923) PubChem (136240914) PubChem (136664747) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (164715984) PubChem (171699466)
4	F, H (A, B)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG) PubChem (888)
5	I (D)	TRIETHYLENE GLYCOL	non-polymer		150.2	1	Chemie (PGE)
6	J, K, L, M (A, B, C, D)	water	water		18.0	226	Chemie (HOH)

Sequence modifications

A, B: 8 - 176 (UniProt: P61294)

PDB	External Database	Details
Gly 4	-	expression tag
Pro 5	-	expression tag
Gly 6	-	expression tag
Ser 7	-	expression tag
Leu 72	Gln 72	engineered mutation

C, D: 849 - 922 (UniProt: Q811U3)

PDB	External Database	Details
Gly 845	-	expression tag
Pro 846	-	expression tag
Gly 847	-	expression tag
Ser 848	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	57133.0
Non-Polymers*	Number of molecules	5
	Total formula weight	1245.1
All*	Total formula weight	58378.2

*Water molecules are not included.