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8IHZ

FACTOR INHIBITING HIF-1 ALPHA in complex with (5-(1-(3-(4-chlorophenyl)propyl)-1H-1,2,3-triazol-4-yl)-3-hydroxypicolinoyl)glycine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Hypoxia-inducible factor 1-alpha inhibitorpolymer34940328.31UniProt (Q9NWT6)
Pfam (PF13621)
Homo sapiens (human)Factor inhibiting HIF-1,FIH-1,Hypoxia-inducible factor asparagine hydroxylase
2B, C, D, E, F...
(A)
SULFATE IONnon-polymer96.114Chemie (SO4)
3O
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
PubChem (32051)
4Q
(A)
2-[[5-[1-[3-(4-chlorophenyl)propyl]-1,2,3-triazol-4-yl]-3-oxidanyl-pyridin-2-yl]carbonylamino]ethanoic acidnon-polymer415.81Chemie (P1X)
PubChem (138319689)
5R
(A)
waterwater18.077Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight40328.3
Non-Polymers*Number of molecules16
Total formula weight1826.1
All*Total formula weight42154.4
*Water molecules are not included.

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PDB entries from 2026-06-24

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