8IFN
MERS-CoV spike trimer in complex with nanobody VHH-T148
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | B, C, E | Spike glycoprotein | polymer | 1347 | 148400.0 | 3 | UniProt (R9UQ53) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) UniProt (by SIFTS) (K9N5Q8) In PDB | Middle East respiratory syndrome-related coronavirus | S glycoprotein,E2,Peplomer protein |
| 2 | A, D, F | VHH-T148 | polymer | 135 | 14802.3 | 3 | Camelus dromedarius | ||
| 3 | G, H, I | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 3 | In PDB GlyTouCan (G81315DD) |
Sequence modifications
B, C, E: 1 - 1333 (UniProt: R9UQ53)
| PDB | External Database | Details |
|---|---|---|
| Ser 748 | Arg 748 | conflict |
| Gly 751 | Arg 751 | conflict |
| Gln 1020 | Arg 1020 | conflict |
| Pro 1060 | Val 1060 | conflict |
| Pro 1061 | Leu 1061 | conflict |
| Gln 1208 | His 1208 | conflict |
| Ser 1291 | - | insertion |
| Arg 1292 | - | insertion |
| Glu 1293 | - | insertion |
| Asn 1294 | - | insertion |
| Leu 1295 | - | insertion |
| Phe 1297 | - | insertion |
| Gln 1298 | - | insertion |
| Gly 1299 | - | insertion |
| Gly 1300 | - | insertion |
| Gly 1301 | Tyr 1292 | conflict |
| Ser 1302 | Asn 1293 | conflict |
| Ala 1303 | Lys 1294 | conflict |
| Gly 1304 | Trp 1295 | conflict |
| Ser 1305 | Pro 1296 | conflict |
| Gly 1306 | Trp 1297 | conflict |
| Pro 1309 | Trp 1300 | conflict |
| Glu 1310 | Leu 1301 | conflict |
| Ala 1311 | Gly 1302 | conflict |
| Pro 1312 | Phe 1303 | conflict |
| Arg 1313 | Ile 1304 | conflict |
| Asp 1314 | Ala 1305 | conflict |
| Gln 1316 | Leu 1307 | conflict |
| Ala 1317 | Val 1308 | conflict |
| Tyr 1318 | Ala 1309 | conflict |
| Val 1319 | Leu 1310 | conflict |
| Arg 1320 | Ala 1311 | conflict |
| Lys 1321 | Leu 1312 | conflict |
| Asp 1322 | Cys 1313 | conflict |
| Gly 1323 | Val 1314 | conflict |
| Glu 1324 | Phe 1315 | conflict |
| Trp 1325 | Phe 1316 | conflict |
| Val 1326 | Ile 1317 | conflict |
| Leu 1328 | Cys 1319 | conflict |
| Ser 1329 | Cys 1320 | conflict |
| Phe 1331 | Gly 1322 | conflict |
| Leu 1332 | Cys 1323 | conflict |
| His 1334 | - | expression tag |
| His 1335 | - | expression tag |
| His 1336 | - | expression tag |
| His 1337 | - | expression tag |
| His 1338 | - | expression tag |
| His 1339 | - | expression tag |
| Trp 1340 | - | expression tag |
| Ser 1341 | - | expression tag |
| His 1342 | - | expression tag |
| Pro 1343 | - | expression tag |
| Gln 1344 | - | expression tag |
| Phe 1345 | - | expression tag |
| Glu 1346 | - | expression tag |
| Lys 1347 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 489607.0 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 2246.0 | |
| All* | Total formula weight | 491853.0 |
