8IDI

Crystal structure of nanobody VHH-T71 with MERS-CoV RBD

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	VHH-T71	polymer	137	14950.3	2		Camelus dromedarius
2	B, D	Spike protein S1	polymer	229	25258.4	2	UniProt (R9UQ53) Pfam (PF09408) UniProt (by SIFTS) (K9N5Q8) In PDB	Middle East respiratory syndrome-related coronavirus (MERS-CoV)	S glycoprotein,E2,Peplomer protein
3	E, F	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-D-mannopyranose-(1-3)][alpha-D-mannopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	2	In PDB
4		water	water		18.0	818	Chemie (HOH)

Sequence modifications

B, D: 367 - 588 (UniProt: R9UQ53)

PDB	External Database	Details
Glu 589	-	expression tag
His 590	-	expression tag
His 591	-	expression tag
His 592	-	expression tag
His 593	-	expression tag
His 594	-	expression tag
His 595	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	80417.4
Branched	Number of molecules	2
	Total formula weight	1821.6
All*	Total formula weight	82239.0

*Water molecules are not included.