8IDF
Crystal structure of human TUT1 complexed with U6 snRNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Speckle targeted PIP5K1A-regulated poly(A) polymerase | polymer | 537 | 58441.3 | 1 | UniProt (Q9H6E5) Pfam (PF12874) Pfam (PF00076) Pfam (PF03828) In PDB | Homo sapiens (human) | Star-PAP,RNA-binding motif protein 21,RNA-binding protein 21,U6 snRNA-specific terminal uridylyltransferase 1,U6-TUTase |
| 2 | B | RNA (53-MER) | polymer | 53 | 17010.1 | 1 | Homo sapiens | ||
| 3 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) |
Sequence modifications
A: 1 - 599 (UniProt: Q9H6E5)
| PDB | External Database | Details |
|---|---|---|
| Ser 19 | Cys 19 | engineered mutation |
| Ala 218 | Asp 218 | engineered mutation |
| - | Ala 235 | deletion |
| - | Pro 236 | deletion |
| - | Glu 237 | deletion |
| - | Ser 238 | deletion |
| - | Pro 239 | deletion |
| - | Ser 240 | deletion |
| - | Leu 241 | deletion |
| - | Asp 242 | deletion |
| - | Ser 243 | deletion |
| - | Ala 244 | deletion |
| - | Leu 245 | deletion |
| - | Ala 246 | deletion |
| - | Ser 247 | deletion |
| - | Pro 248 | deletion |
| - | Leu 249 | deletion |
| - | Asp 250 | deletion |
| - | Pro 251 | deletion |
| - | Gln 252 | deletion |
| - | Ala 253 | deletion |
| - | Leu 254 | deletion |
| - | Ala 255 | deletion |
| - | Cys 256 | deletion |
| - | Thr 257 | deletion |
| - | Pro 258 | deletion |
| - | Ala 259 | deletion |
| - | Ser 260 | deletion |
| - | Pro 261 | deletion |
| - | Pro 262 | deletion |
| - | Asp 263 | deletion |
| - | Ser 264 | deletion |
| - | Gln 265 | deletion |
| - | Pro 266 | deletion |
| - | Pro 267 | deletion |
| - | Ala 268 | deletion |
| - | Ser 269 | deletion |
| - | Pro 270 | deletion |
| - | Gln 271 | deletion |
| - | Asp 272 | deletion |
| - | Ser 273 | deletion |
| - | Glu 274 | deletion |
| - | Ala 275 | deletion |
| - | Leu 276 | deletion |
| - | Asp 277 | deletion |
| - | Phe 278 | deletion |
| - | Glu 279 | deletion |
| - | Thr 280 | deletion |
| - | Pro 281 | deletion |
| - | Ser 282 | deletion |
| - | Ser 283 | deletion |
| - | Ser 284 | deletion |
| - | Leu 285 | deletion |
| - | Ala 286 | deletion |
| - | Pro 287 | deletion |
| - | Gln 288 | deletion |
| - | Thr 289 | deletion |
| - | Pro 290 | deletion |
| - | Asp 291 | deletion |
| - | Ser 292 | deletion |
| - | Ala 293 | deletion |
| - | Leu 294 | deletion |
| - | Ala 295 | deletion |
| - | Ser 296 | deletion |
| - | Glu 297 | deletion |
| - | Thr 298 | deletion |
| - | Leu 299 | deletion |
| - | Ala 300 | deletion |
| - | Ser 301 | deletion |
| - | Pro 302 | deletion |
| - | Gln 303 | deletion |
| - | Ser 304 | deletion |
| Ala 372 | Cys 372 | engineered mutation |
| Ala 399 | Cys 399 | engineered mutation |
| Ala 415 | Cys 415 | engineered mutation |
| Ala 501 | Cys 501 | engineered mutation |
| Ser 504 | Cys 504 | engineered mutation |
| Ala 574 | Cys 574 | engineered mutation |
| Leu 600 | - | expression tag |
| Glu 601 | - | expression tag |
| His 602 | - | expression tag |
| His 603 | - | expression tag |
| His 604 | - | expression tag |
| His 605 | - | expression tag |
| His 606 | - | expression tag |
| His 607 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 75451.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 65.4 | |
| All* | Total formula weight | 75516.8 |
