8IBQ
Bromodomain and Extra-terminal Domain (BET) BRD4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bromodomain-containing protein 4 | polymer | 123 | 14653.0 | 1 | UniProt (O60885) Pfam (PF00439) | Homo sapiens (human) | Protein HUNK1 |
| 2 | B (A) | 7-[2-fluoranyl-3-(1,3,5-trimethylpyrazol-4-yl)phenyl]-1~{H}-imidazo[4,5-b]pyridine | non-polymer | 321.4 | 1 | Chemie (OWO) | |||
| 3 | C (A) | water | water | 18.0 | 58 | Chemie (HOH) |
Sequence modifications
A: 44 - 165 (UniProt: O60885)
| PDB | External Database | Details |
|---|---|---|
| Met 43 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 14653.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 321.4 | |
| All* | Total formula weight | 14974.3 |
