8IAK
Cryo-EM structure of the yeast SPT-ORM2 (ORM2-S3A-N71A) complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E (A, E) | Long chain base biosynthesis protein 1,Serine palmitoyltransferase 1 | polymer | 534 | 59354.7 | 2 | UniProt (Q94IB8) UniProt (P25045) Pfam (PF00155) | Arabidopsis thaliana (thale cress) | |
| 2 | B, F (B, F) | Serine palmitoyltransferase 2 | polymer | 561 | 63417.8 | 2 | UniProt (P40970) Pfam (PF00155) | Saccharomyces cerevisiae (brewer's yeast) | SPT 2,Long chain base biosynthesis protein 2 |
| 3 | C, G (D, H) | Protein ORM2 | polymer | 216 | 24787.6 | 2 | UniProt (Q06144) Pfam (PF04061) | Saccharomyces cerevisiae S288C | |
| 4 | D, H (C, G) | Serine palmitoyltransferase-regulating protein TSC3 | polymer | 80 | 9590.2 | 2 | UniProt (Q3E790) | Saccharomyces cerevisiae (brewer's yeast) | Temperature-sensitive CSG2-mutant suppressor protein 3 |
Sequence modifications
A, E: 25 - 101 (UniProt: Q94IB8)
A, E: 102 - 558 (UniProt: P25045)
D, H: 1 - 216 (UniProt: Q06144)
A, E: 102 - 558 (UniProt: P25045)
D, H: 1 - 216 (UniProt: Q06144)
| PDB | External Database | Details |
|---|---|---|
| Ala 46 | Ser 46 | engineered mutation |
| Ala 47 | Ser 47 | engineered mutation |
| Ala 48 | Ser 48 | engineered mutation |
| Ala 71 | Asn 71 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 314300.6 | |
| All* | Total formula weight | 314300.6 |
