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8I6V

Cryo-EM structure of the polyphosphate polymerase VTC complex(Vtc4/Vtc3/Vtc1)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
Vacuolar transporter chaperone complex subunit 1polymer12914388.13UniProt (P40046)
Pfam (PF02656)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Negative regulator of CDC42 protein 1,Phosphate metabolism protein 4,SPX-dependent polyphosphate polymerase VTC subunit 1,Vacuolar membrane polyphosphate polymerase accessory subunit 1,PolyP polymerase
2D
(D)
Vacuolar transporter chaperone 3 complex subunit 3polymer83596684.31UniProt (Q02725)
Pfam (PF09359)
Pfam (PF02656)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Phosphate metabolism protein 2,SPX-dependent polyphosphate polymerase VTC subunit 3,Vacuolar membrane polyphosphate polymerase accessory subunit 3,PolyP polymerase
3E
(E)
Vacuolar transporter chaperone complex subunit 4polymer72183268.71UniProt (P47075)
Pfam (PF09359)
Pfam (PF02656)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Phosphate metabolism protein 3,Polyphosphate kinase,SPX-dependent polyphosphate polymerase VTC subunit 4,Vacuolar membrane polyphosphate polymerase catalytic subunit,PolyP polymerase
4F
(C)
(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphatenon-polymer760.11Chemie (POV)
5G, H, K
(D, E)
PHOSPHATE IONnon-polymer95.03Chemie (PO4)
6I
(E)
TRIPHOSPHATEnon-polymer258.01Chemie (3PO)
7J
(E)
MANGANESE (II) IONnon-polymer54.91Chemie (MN)
8L, M
(D, E)
waterwater18.04Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight223117.1
Non-Polymers*Number of molecules6
Total formula weight1357.9
All*Total formula weight224475.0
*Water molecules are not included.

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PDB entries from 2026-01-14

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