8I5Z
LDH Mutant P101Q-(An unexpected single-point mutation triggers the unleashing of catalytic potential of a NADH-dependent dehydrogenase)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein | polymer | 339 | 37711.3 | 4 | UniProt (F8A9V0) Pfam (PF00389) Pfam (PF02826) In PDB | Thermodesulfatator indicus DSM 15286 | lactate dehydrogenase |
2 | water | water | 18.0 | 214 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 325 (UniProt: F8A9V0)
PDB | External Database | Details |
---|---|---|
Met -13 | - | initiating methionine |
Gly -12 | - | expression tag |
Ser -11 | - | expression tag |
Ser -10 | - | expression tag |
His -9 | - | expression tag |
His -8 | - | expression tag |
His -7 | - | expression tag |
His -6 | - | expression tag |
His -5 | - | expression tag |
His -4 | - | expression tag |
Ser -3 | - | expression tag |
Gln -2 | - | expression tag |
Asp -1 | - | expression tag |
Pro 0 | - | expression tag |
Gln 101 | Pro 101 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 150845.2 | |
All* | Total formula weight | 150845.2 |