8I17
Structural basis for H2A-H2B recognitions by human Spt16
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (A, D, G) | Histone H2A type 1-B/E | polymer | 100 | 11014.8 | 3 | UniProt (P04908) Pfam (PF00125) Pfam (PF16211) | Homo sapiens (human) | Histone H2A.2,Histone H2A/a,Histone H2A/m |
| 2 | B, D, F (B, E, H) | Histone H2B type 1-J | polymer | 100 | 11253.0 | 3 | UniProt (P06899) Pfam (PF00125) | Homo sapiens (human) | Histone H2B.1,Histone H2B.r,H2B/r |
| 3 | G, H, I (F, I, C) | FACT complex subunit SPT16 | polymer | 42 | 4669.3 | 3 | UniProt (Q9Y5B9) Pfam (PF21091) | Homo sapiens (human) | Chromatin-specific transcription elongation factor 140 kDa subunit,FACT 140 kDa subunit,FACTp140,Facilitates chromatin transcription complex subunit SPT16,hSPT16 |
| 4 | J, K (A, E) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 5 | L, M, N, O, P... (A, B, D, E, G...) | water | water | 18.0 | 96 | Chemie (HOH) |
Sequence modifications
B, E, H: 27 - 125 (UniProt: P06899)
F, I, C: 926 - 965 (UniProt: Q9Y5B9)
| PDB | External Database | Details |
|---|---|---|
| Ser 26 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 924 | - | expression tag |
| Pro 925 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 80811.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 70.9 | |
| All* | Total formula weight | 80882.1 |
