8I0K
Cryo-electron microscopic structure of the 2-oxoglutarate dehydrogenase(E1) with TCAIM complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 2-oxoglutarate dehydrogenase complex component E1 | polymer | 911 | 103809.3 | 2 | UniProt (Q02218) Pfam (PF00676) Pfam (PF02779) Pfam (PF16870) | Homo sapiens (human) | E1o,OGDC-E1,OGDH-E1,2-oxoglutarate dehydrogenase,mitochondrial,Alpha-ketoglutarate dehydrogenase,Alpha-KGDH-E1,Thiamine diphosphate (ThDP)-dependent 2-oxoglutarate dehydrogenase |
| 2 | C (C) | T-cell activation inhibitor, mitochondrial | polymer | 302 | 35402.1 | 1 | UniProt (Q8N3R3) Pfam (PF14688) | Homo sapiens (human) | Tolerance associated gene-1 protein,TOAG-1 |
| 3 | D, F (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | E (A) | THIAMINE DIPHOSPHATE | non-polymer | 425.3 | 1 | Chemie (TPP) | |||
| 5 | G (B) | 2-[3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-2H-1,3-thiazol-5-yl]ethyl phosphono hydrogen phosphate | non-polymer | 426.3 | 1 | Chemie (8EL) | |||
| 6 | H (B) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 243020.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 940.3 | |
| All* | Total formula weight | 243961.0 |
