8HYI
Crystal structure of human P-cadherin MEC12 (X dimer) in complex with 2-(2-methyl-5-phenyl-1H-indole-3-yl)ethan-1-amine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Cadherin-3 | polymer | 214 | 23422.0 | 2 | UniProt (P22223) Pfam (PF00028) In PDB | Homo sapiens (human) | Placental cadherin,P-cadherin |
| 2 | A | 2-(2-methyl-5-phenyl-1H-indole-3-yl)ethan-1-amine | non-polymer | 250.3 | 2 | Chemie (22R) | |||
| 3 | A, B | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 2 | Chemie (DMS) | |||
| 4 | A, B | CALCIUM ION | non-polymer | 40.1 | 6 | Chemie (CA) |
Sequence modifications
A, B: 1 - 213 (UniProt: P22223)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 46844.0 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 897.4 | |
| All* | Total formula weight | 47741.4 |
