8HXC

Cryo-EM structure of MPXV M2 heptamer in complex with human B7.2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	NFkB inhibitor	polymer	203	23285.3	7	UniProt (Q3I8Y9) Pfam (PF04887) UniProt (by SIFTS) (A0A7H0DN11)	Monkeypox virus
2	H, I, J, K, L... (H, I, J, K, L...)	T-lymphocyte activation antigen CD86	polymer	213	24420.6	7	UniProt (P42081) Pfam (PF07686)	Homo sapiens (human)	Activation B7-2 antigen,B70,BU63,CTLA-4 counter-receptor B7.2,FUN-1

Contents of the asymmetric unit

Polymers	Number of chains	14
	Total formula weight	333942.0
All*	Total formula weight	333942.0

*Water molecules are not included.