8HXC

Cryo-EM structure of MPXV M2 heptamer in complex with human B7.2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0019049	biological_process	virus-mediated perturbation of host defense response
A	0044165	cellular_component	host cell endoplasmic reticulum
A	0085034	biological_process	symbiont-mediated suppression of host NF-kappaB cascade
B	0005576	cellular_component	extracellular region
B	0019049	biological_process	virus-mediated perturbation of host defense response
B	0044165	cellular_component	host cell endoplasmic reticulum
B	0085034	biological_process	symbiont-mediated suppression of host NF-kappaB cascade
C	0005576	cellular_component	extracellular region
C	0019049	biological_process	virus-mediated perturbation of host defense response
C	0044165	cellular_component	host cell endoplasmic reticulum
C	0085034	biological_process	symbiont-mediated suppression of host NF-kappaB cascade
D	0005576	cellular_component	extracellular region
D	0019049	biological_process	virus-mediated perturbation of host defense response
D	0044165	cellular_component	host cell endoplasmic reticulum
D	0085034	biological_process	symbiont-mediated suppression of host NF-kappaB cascade
E	0005576	cellular_component	extracellular region
E	0019049	biological_process	virus-mediated perturbation of host defense response
E	0044165	cellular_component	host cell endoplasmic reticulum
E	0085034	biological_process	symbiont-mediated suppression of host NF-kappaB cascade
F	0005576	cellular_component	extracellular region
F	0019049	biological_process	virus-mediated perturbation of host defense response
F	0044165	cellular_component	host cell endoplasmic reticulum
F	0085034	biological_process	symbiont-mediated suppression of host NF-kappaB cascade
G	0005576	cellular_component	extracellular region
G	0019049	biological_process	virus-mediated perturbation of host defense response
G	0044165	cellular_component	host cell endoplasmic reticulum
G	0085034	biological_process	symbiont-mediated suppression of host NF-kappaB cascade

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	28
Details	CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255|PROSITE-ProRule:PRU00498

Chain	Residue	Details
A	ASN49
C	ASN79
C	ASN118
C	ASN154
D	ASN49
D	ASN79
D	ASN118
D	ASN154
E	ASN49
E	ASN79
E	ASN118
A	ASN79
E	ASN154
F	ASN49
F	ASN79
F	ASN118
F	ASN154
G	ASN49
G	ASN79
G	ASN118
G	ASN154
K	ASN154
A	ASN118
K	ASN177
K	ASN192
K	ASN213
L	ASN33
L	ASN47
L	ASN135
L	ASN146
L	ASN154
L	ASN177
L	ASN192
A	ASN154
L	ASN213
M	ASN33
M	ASN47
M	ASN135
M	ASN146
M	ASN154
M	ASN177
M	ASN192
M	ASN213
N	ASN33
B	ASN49
N	ASN47
N	ASN135
N	ASN146
N	ASN154
N	ASN177
N	ASN192
N	ASN213
B	ASN79
B	ASN118
B	ASN154
C	ASN49

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