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8HXC

Cryo-EM structure of MPXV M2 heptamer in complex with human B7.2

Functional Information from GO Data
ChainGOidnamespacecontents
A0005576cellular_componentextracellular region
A0044165cellular_componenthost cell endoplasmic reticulum
A0085034biological_processsymbiont-mediated suppression of host NF-kappaB cascade
B0005576cellular_componentextracellular region
B0044165cellular_componenthost cell endoplasmic reticulum
B0085034biological_processsymbiont-mediated suppression of host NF-kappaB cascade
C0005576cellular_componentextracellular region
C0044165cellular_componenthost cell endoplasmic reticulum
C0085034biological_processsymbiont-mediated suppression of host NF-kappaB cascade
D0005576cellular_componentextracellular region
D0044165cellular_componenthost cell endoplasmic reticulum
D0085034biological_processsymbiont-mediated suppression of host NF-kappaB cascade
E0005576cellular_componentextracellular region
E0044165cellular_componenthost cell endoplasmic reticulum
E0085034biological_processsymbiont-mediated suppression of host NF-kappaB cascade
F0005576cellular_componentextracellular region
F0044165cellular_componenthost cell endoplasmic reticulum
F0085034biological_processsymbiont-mediated suppression of host NF-kappaB cascade
G0005576cellular_componentextracellular region
G0044165cellular_componenthost cell endoplasmic reticulum
G0085034biological_processsymbiont-mediated suppression of host NF-kappaB cascade
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues28
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine; by host","evidences":[{"source":"PROSITE-ProRule","id":"PRU00498","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues686
DetailsDomain: {"description":"Ig-like V-type"}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues14
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

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PDB entries from 2025-07-30

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