8HW2

Cryo-EM structure of beta-estradiol 17-(beta-D-glucuronide)-bound human ABC transporter ABCC3 in nanodiscs

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	ATP-binding cassette sub-family C member 3	polymer	1527	169504.7	1	UniProt (O15438) Pfam (PF00664) Pfam (PF00005) In PDB	Homo sapiens (human)	Canalicular multispecific organic anion transporter 2,Multi-specific organic anion transporter D,MOAT-D,Multidrug resistance-associated protein 3
2	A	Estradiol-17beta-glucuronide	non-polymer		448.5	2	Chemie (U38)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	169504.7
Non-Polymers*	Number of molecules	2
	Total formula weight	897.0
All*	Total formula weight	170401.7

*Water molecules are not included.