8HUO
X-ray structure of human PPAR delta ligand binding domain-seladelpar co-crystals obtained by co-crystallization
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Peroxisome proliferator-activated receptor delta | polymer | 276 | 31527.6 | 2 | UniProt (Q03181) Pfam (PF00104) In PDB | Homo sapiens (human) | PPAR-delta,NUCI,Nuclear hormone receptor 1,NUC1,Nuclear receptor subfamily 1 group C member 2,Peroxisome proliferator-activated receptor beta,PPAR-beta |
2 | A, B | Seladelpar | non-polymer | 444.5 | 2 | Chemie (KKB) |
Sequence modifications
A, B: 170 - 441 (UniProt: Q03181)
PDB | External Database | Details |
---|---|---|
Gly 166 | - | expression tag |
Ser 167 | - | expression tag |
His 168 | - | expression tag |
Met 169 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 63055.3 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 888.9 | |
All* | Total formula weight | 63944.2 |