8HUK
X-ray structure of human PPAR alpha ligand binding domain-lanifibranor-SRC1 coactivator peptide co-crystals obtained by soaking
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | Peroxisome proliferator-activated receptor alpha | polymer | 273 | 30856.1 | 2 | UniProt (Q07869) Pfam (PF00104) In PDB | Homo sapiens (human) | |
2 | B | 15-meric peptide from Nuclear receptor coactivator 1 | polymer | 15 | 1848.2 | 1 | UniProt (Q15788) In PDB | Homo sapiens | |
3 | C | 4-[1-(1,3-benzothiazol-6-ylsulfonyl)-5-chloro-indol-2-yl]butanoic acid | non-polymer | 434.9 | 1 | Chemie (BJB) |
Sequence modifications
A, C: 200 - 468 (UniProt: Q07869)
PDB | External Database | Details |
---|---|---|
Gly 196 | - | expression tag |
Ser 197 | - | expression tag |
His 198 | - | expression tag |
Met 199 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 63560.3 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 434.9 | |
All* | Total formula weight | 63995.2 |