8HUK
X-ray structure of human PPAR alpha ligand binding domain-lanifibranor-SRC1 coactivator peptide co-crystals obtained by soaking
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003677 | molecular_function | DNA binding |
A | 0004879 | molecular_function | nuclear receptor activity |
A | 0005634 | cellular_component | nucleus |
A | 0006355 | biological_process | regulation of DNA-templated transcription |
C | 0003677 | molecular_function | DNA binding |
C | 0004879 | molecular_function | nuclear receptor activity |
C | 0005634 | cellular_component | nucleus |
C | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 6 |
Details | BINDING: BINDING => ECO:0000269|PubMed:19116277, ECO:0007744|PDB:3ET1 |
Chain | Residue | Details |
A | SER280 | |
A | TYR314 | |
A | TYR464 | |
C | SER280 | |
C | TYR314 | |
C | TYR464 |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | SITE: Essential for heterodimerization with RXRA |
Chain | Residue | Details |
A | LEU433 | |
C | LEU433 |