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8HTA

Solution Structure of the C65A/C167A Mutant of Human Lipocalin-type Prostaglandin D Synthase

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Prostaglandin-H2 D-isomerasepolymer17018797.01UniProt (P41222)
Pfam (PF00061)
Homo sapiens (human)Beta-trace protein,Cerebrin-28,Glutathione-independent PGD synthase,Lipocalin-type prostaglandin-D synthase,L-PGDS,Prostaglandin-D2 synthase,PGD2 synthase,PGDS,PGDS2
Sequence modifications
A: 23 - 190 (UniProt: P41222)
PDBExternal DatabaseDetails
Gly 21-expression tag
Ser 22-expression tag
Ala 65Cys 65engineered mutation
Ala 167Cys 167engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight18797.0
All*Total formula weight18797.0
*Water molecules are not included.

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PDB entries from 2025-07-02

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