8HSV

The structure of rat beta-arrestin1 in complex with a rat Mdm2 peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, B)	Beta-arrestin-1	polymer	414	46505.8	2	UniProt (P29066) Pfam (PF00339) Pfam (PF02752)	Rattus norvegicus (Norway rat)	Arrestin beta-1
2	B, D (E, F)	peptide from E3 ubiquitin-protein ligase Mdm2	polymer	18	1907.9	2	UniProt (D3ZVH5) UniProt (by SIFTS) (A0A8I6G5V3)	Rattus norvegicus
3	E, F, G, H, I (A, B)	SULFATE ION	non-polymer		96.1	5	Chemie (SO4)
4	J, K (A, B)	water	water		18.0	88	Chemie (HOH)

Sequence modifications

A, B: 1 - 394 (UniProt: P29066)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Val 59	Cys 59	engineered mutation
Ser 125	Cys 125	engineered mutation
Leu 140	Cys 140	engineered mutation
Val 150	Cys 150	engineered mutation
Val 242	Cys 242	engineered mutation
Val 251	Cys 251	engineered mutation
Ser 269	Cys 269	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	96827.3
Non-Polymers*	Number of molecules	5
	Total formula weight	480.3
All*	Total formula weight	97307.6

*Water molecules are not included.