8HRZ
Crystal structure of the p97-N/D1 hexamer in complex with six p47-UBX domains
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | Transitional endoplasmic reticulum ATPase | polymer | 438 | 48904.1 | 12 | UniProt (P55072) Pfam (PF02359) Pfam (PF02933) Pfam (PF00004) Pfam (PF17862) In PDB | Homo sapiens (human) | TER ATPase,15S Mg(2+)-ATPase p97 subunit,Valosin-containing protein,VCP |
2 | M, N, O, P, Q... | NSFL1 cofactor p47 | polymer | 85 | 9575.0 | 12 | UniProt (Q9UNZ2) Pfam (PF00789) In PDB | Homo sapiens (human) | UBX domain-containing protein 2C,p97 cofactor p47 |
3 | C, D, E, F, G... | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 12 | Chemie (ADP) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L: 21 - 458 (UniProt: P55072)
M, N, O, P, Q, R, S, T, U, V, W, X: 287 - 370 (UniProt: Q9UNZ2)
PDB | External Database | Details |
---|---|---|
Ala 294 | Glu 294 | engineered mutation |
Ala 295 | Lys 295 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Met 286 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 24 |
Total formula weight | 701749.7 | |
Non-Polymers* | Number of molecules | 12 |
Total formula weight | 5126.4 | |
All* | Total formula weight | 706876.1 |